Dual endothelin-1/angiotensin II receptor

Dual endothelin-1/angiotensin-2 receptor that is functionally coupled to a calcium-mobilizing transduction system, responding equivalently to both endothelin-1/EDN1 and angiotensin-2 peptides in a highly specific manner. Also binds the signal peptide of VEGFA. May play a role in angiogenesis with a significant role in cardiovascular and neural development (By similarity).

PDB Code:
Native
Stable
Pure
Active protein
Recombinant protein
Human Origin
Entry name:
DEAR_HUMAN
Gene name:
FBXW7-AS1
Uniprot accession:
B0L3A2
Origin:
Homo sapiens (Human)
Protein family:
nd
Full-length:
85
Mass:
9677
Sequence:
MTMFKGSNEMKSRWNWGSITCIICFTCVGSQLSMSSSKASNFSGPLQLYQRELEIFIVLTDVPNYRLIKENSHLHTTIVDQGRTV
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Expression systems: bacteria, yeast, insect cells, HEK & CHO mammalian cells
Purified formats: detergents, SMALPs, nanodiscs, proteoliposomes

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