Protein TUNAR
In neurons, plays a role in the regulation of intracellular Ca(2+), possibly by acting as an activator of ATP2A2/SERCA2, thus increasing the efficiency with which Ca(2+) is removed from the cytoplasm (By similarity). Inhibits differentiation of embryonic stem cells into neurons and inhibits neurite outgrowth, likely as a result of its role in intracellular Ca(2+) regulation (By similarity). In pancreatic beta cells, lowers Ca(2+) levels in the endoplasmic reticulum and enhances glucose-stimulated insulin secretion.
PDB Code:
Native
Stable
Pure
Active protein
Recombinant protein
Human Origin
Entry Name:
TUNAR_HUMAN
Gene Name:
TUNAR
Uniprot Accession:
A0A1B0GTB2
Origin:
Homo sapiens (Human)
Protein family:
nd
Full-length:
48
Mass:
5360
Sequence:
MVITSENDEDRGGQEKESKEESVLAMLGIIGTILNLIVIIFVYIYTTL