Home
Services
Production
Design your project

Design your project

Your target / construct

Calixar offers multiple cleavable tags (His, Flag, Strep, Avi…) and/or protein-fusion (GFP, RFP…), and will assist you to select optimal options for your project.

Your production process

Calixar’s purification process includes solubilization and stabilization screening in various proprietary and commercial detergents and/or SMALPs. 1- or 2-step affinity purification followed by a size-exclusion chromatography ensures >90% purity degree.

Calixar’s quality control process includes:
✓ Purity evaluation
‍✓ Protein quantification
‍✓ Homogeneity determination
✓ Cryo-stability assay

‍In addition, Calixar can develop specific protein characterizations such as:
• Thermal shift assay
‍• Functional assay (enzymatic activity, proteoliposome ion flux assay
• Ligand binding assay (radiobinding, fluorescence polarization, microscale thermophoresis

From µg- to mg-scale production, Calixar will fit all your needs of proteins for your R&D developments.
Based on your final application, Calixar is able to deliver your purified target in various formats such as micelles of detergent, SMALPs, amphipols, nanodiscs and proteoliposomes.

Your information

Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.

Services

Production
Expression
Isolation
Design your project
Analysis
Ligand binding assays
Thermal stability assays
Identification
Conformational antibody development
Vaccine development
Ligand high-throughput screening
Structure-based drug discovery
Immunoassays
Deorphanization projects
Identification of relevant targets
Expression of full-length membrane proteins
Functional isolation and stabilization of targets
Conformational antibody development
Vaccine development
High-throughput ligand screening
Structure-based drug discovery
Immunoassays
Deorphanization projects
Identification of relevant targets
Expression of full-length membrane proteins
Functional isolation and stabilization of targets

Secure and boost
your discovery programs.

Starting from native material or recombinant systems, we succeed with all types of membrane proteins: GPCRs, Ion Channels, Transporters, Receptors and Viral Proteins.

Contact us