ODG Reagent
IUPAC name: N-(2-methyl-1,3-bis(O-β-D-Glucose)propan-2-yl)-3-(octylthio)propanamide
Compound name: ODG
Catalogue number: ODG_100MG
ODG_250MG
ODG_500MG
ODG_1G
Molec. Formula: C27H51NO13S
CAS: nd
MW: 629.8 g/mol
pKa: na
Percent Composition: C, 51.49; H, 8.16; N, 2.22; O, 33.03; S, 5.09
Physical state: White powder
Purity (HPLC, 214nm): ≥95%
Retention time (RP18 HPLC)b: tR = 12.9 min
CMC: >10 mM
Exact mass: 629.3081
Stability: Store in <-20°C freezer out of direct light
Solubility Structure: Soluble in water (0.5M), methanol and DMSO.
We use a novel & tailored approach to give you an edge
CALIXAR’s ODG is manufactured in a powder form and is used in aqueous solution or buffer. ODG can be processed with biological materials (biological membranes).
Our clients are able to use ODG to help produce lipid detergents, mixed micelles, and protein detergent micelles. ODG allows clients to extract, to solubilize and to stabilize native and functional membrane proteins in solution.
CALIXAR’s ODG is very mild detergent to extract, to solubilize and to stabilize native membrane proteins and is non-ionic. Accordingly, it is not sensitive to ionic concentration or pH fluctuations which is excellent to extract, to solubilize and to stabilize specific membrane proteins.
Our ODG can extract, solubilize and stabilize more efficiently delicate membrane proteins of high medical relevance.
Proprietary mild detergent
CALIXAR’s ODG is non-ionic and therefore is not receptive to ionic strength or pH variations and could be well adapted to extract, to solubilize and to stabilize specific membrane proteins.
Specifically made for Biotech
CLAIXAR’s ODG extract high-quality membrane proteins used for research, drug discovery including structural studies and are adapted for use in pharmaceutical, biotechnology companies, as well as for academic teams (biochemists, structural biologists, pharmacologists, virologists) that are involved in the life science fields.
For any Life Science Project
- Antibodies (including nanobodies, scaffold proteins, aptamers)
- Small molecules
- 3D Structures (cryoEM, XRay crystallography, NMR, SANS, SAXS)
- Drug discovery (Screening: HTS, FBDD, SBDD; Hit and lead validation)
- Antibody discovery (Immunization and display technologies)
- Clinical stage
References
Hydrogenated Diglucose Detergents for Membrane-Protein Extraction and Stabilization
