CALIXAR’s DLAC is provided to clients in a powder form and is used in aqueous solutions or buffers. DLAC can be processed with biological materials (biological membranes).
Our clients are able to use DLAC to better produce lipid detergents, mixed micelles, and protein detergent micelles. DLAC provides our clients with a way to extract, to solubilize and to stabilize native and functional membrane proteins.
DLAC is a quite mild detergent to extract, to solubilize and to stabilize native membrane proteins. As DLAC is non-ionic. Therefore, it is not sensitive to ionic strength or pH variations which is ideal to extract, to solubilize and to stabilize specific membrane proteins of high medical relevance.
- Antibodies (including nanobodies, scaffold proteins, aptamers)
- Small molecules
- 3D Structures (cryoEM, XRay crystallography, NMR, SANS, SAXS)
- Drug discovery (Screening: HTS, FBDD, SBDD; Hit and lead validation)
- Antibody discovery (Immunization and display technologies)
- Clinical stage