Soft proprietary detergents

DDG reagent

CALIXAR’s DDG reagent is a non-ionic amphiphilic detergent and surfactant with a di-glucose polar group and decyl chain.
€ 198.00 (100mg)
€ 363.00 (250mg)

IUPAC name: N-(2-methyl-1,3-bis(O-β-D-Glucose)propan-2-yl)-3-(decylthio)propanamide

Compound name: DDG

Catalogue number: DDG_100MG,

Molec. Formula: C29H55NO13S

CAS: nd

MW: 657.8 g/mol

pKa: na​

Percent Composition: C, 52.95; H, 8.43; N, 2.13; O, 31.62; S, 4.87


Physical state: White powder

Purity (HPLC, 214nm): ≤95%

Retention time (RP18 HPLC)b: tR = 14.6 min

CMC: >0.54 mM

Exact mass: 657.3394

Stability: Store in <-20°C out of direct light

Solubility Structure: Soluble in water (27mM), methanol and DMSO

What makes us special

We employ a unique & tailor-made method to give you the edge

Calixar’s DDG is in a powder application and is used in an aqueous solution or buffer. DDG can be coupled with biological elements (biological membranes).

Our clients use DDG to help create lipids-detergents mixed micelles, and protein detergent micelles. DDG empowers clients to extract, to solubilize and to stabilize native and functional membrane proteins.

DDG is a very moderate detergent used to extract, solubilize and stabilize native membrane proteins non-ionically. Consequently, it is not sensitive to ionic strength or pH variations which are ideal to extract, to solubilize and to stabilize specific membrane proteins of exceptional medical relevance.

Proprietary mild detergent

CALIXAR’s DDG is non-ionic and hence is not sensitive to ionic strengths or pH variations. It is well conformed to extract, to solubilize and to stabilize specific membrane proteins.

Specifically made for Biotech

CALIXAR’s DDG extract high-quality membrane proteins used for research, drug discovery including structural studies and are adapted for use in pharmaceutical, biotechnology companies, as well as for academic teams (biochemists, structural biologists, pharmacologists, virologists) that are involved in the life science fields.

For any Life Science Project
  • Antibodies (including nanobodies, scaffold proteins, aptamers)
  • Small molecules
  • 3D Structures (cryoEM, XRay crystallography, NMR, SANS, SAXS)
  • Drug discovery (Screening: HTS, FBDD, SBDD; Hit and lead validation)
  • Antibody discovery (Immunization and display technologies)
  • Clinical stage
More documentation



Micellar and biochemical properties of a propyl-ended fluorinated surfactant designed for membrane-protein study

Abla M et al. 2015

Hydrogenated Diglucose Detergents for Membrane-Protein Extraction and Stabilization

Guillet P. et al. 2019

Glucose-Based Surfactants with Hydrogenated, Fluorinated, or Hemifluorinated Tails: Synthesis and Comparative Physical-Chemical Characterization

Abla M et al. 2008

Secure and boost
your discovery programs.

Starting from native material or recombinant systems, we succeed with all types of membrane proteins: GPCRs, Ion Channels, Transporters, Receptors and Viral Proteins.