Calixar’s DDG is in a powder application and is used in an aqueous solution or buffer. DDG can be coupled with biological elements (biological membranes).
Our clients use DDG to help create lipids-detergents mixed micelles, and protein detergent micelles. DDG empowers clients to extract, to solubilize and to stabilize native and functional membrane proteins.
DDG is a very moderate detergent used to extract, solubilize and stabilize native membrane proteins non-ionically. Consequently, it is not sensitive to ionic strength or pH variations which are ideal to extract, to solubilize and to stabilize specific membrane proteins of exceptional medical relevance.
- Antibodies (including nanobodies, scaffold proteins, aptamers)
- Small molecules
- 3D Structures (cryoEM, XRay crystallography, NMR, SANS, SAXS)
- Drug discovery (Screening: HTS, FBDD, SBDD; Hit and lead validation)
- Antibody discovery (Immunization and display technologies)
- Clinical stage