CALX8 Reagent
5,11,17-tris[(carboxy)methyl]-25-monooctyloxy-26,27,28-trihydroxycalix[4]arene
Compound name: CALX8
Catalogue number: CALX8_50MG, CALX8_100MG, CALX8_250MG
Molec. Formula: C42H43Na3O10
CAS: nd
MW: 776.7 g/mol p
Ka: na
Percent Composition: C, 64.94; H, 5.58; N, 8.88; O, 20.60
Physical state: Beige powder
Purity (HPLC, 214nm): nd
Retention time (RP18 HPLC): nd
CMC: 0.85 mM
Exact mass: 776.2549
Stability: Store in <-20°C out of direct light
Solubility Structure: Soluble in methanol, DMSO and water
We employ a unique & custom-made procedure to award us the edge
The Calixarene platform and carboxylic groups help to stabilize native membrane proteins and the alkyl chain serves to extract native membrane proteins at the same time.
CALIXAR’s CALX8 is in powder form and is used in an aqueous solution or buffer. CALX8 can be combined with biological materials (such as biological membranes).
Our clients are able to use CALX8 to assist in the development of lipids-detergents mixed micelles, and protein detergent micelles. CALX8 enables clients to extract, solubilize and stabilize native and functional membrane proteins in a solution.
CALX8 is very mild detergent to secure, to solubilize and to preserve native membrane proteins which is ideal for extraction, to solubilization and to stabilization of particular membrane proteins.
Proprietary mild detergent
CALIXAR’s CALX8 is adapted to extract, to solubilize or to stabilize precise membrane proteins.
Specifically made for Biotech
CALIXAR’s CALX8 extracts high-quality membrane proteins that are utilized for pharmaceutical research, discovery and, structural studies. Our CALX8 is used by biotechnology companies, as well as for academic teams (biochemists, structural biologists, pharmacologists, virologists) that are involved in the life science fields.
For any Life Science Project
- Antibodies (including nanobodies, scaffold proteins, aptamers)
- Small molecules
- 3D Structures (cryoEM, XRay crystallography, NMR, SANS, SAXS)
- Drug discovery (Screening: HTS, FBDD, SBDD; Hit and lead validation)
- Antibody discovery (Immunization and display technologies)
- Clinical stage