Solubilization and Stabilization of Native Membrane Proteins for Drug Discovery
December 16, 2020
To study the structural and functional aspect of membrane proteins, extraction is a critical step that represents the main obstacle for membrane proteins biochemistry and structural biology. Information described in this chapter, co-written by Vincent Corvest, Senior Scientist at CALIXAR, can be useful for all researcher teams and companies working in this field.
CALIXAR is a French company very active in the domain of membrane proteins. Thanks to its unique and patented technological platform, CALIXAR is able to isolate in solution native full-length membrane proteins, while keeping their structural and functional integrity. With this high quality, membrane targets are often the key for successful discovery programs.