New publication on Integral Membrane Protein Oligomers Isolation

June 23, 2020

This research work illustrates the advantage of using CALIXAR’s approach to isolate and characterize integral membrane protein oligomers such as this reported case study of the Transmembrane Chemokine CX3CL1.

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Conformational antibody development

Vaccine development

Ligand high-throughput screening

Structure-based drug discovery

Immunoassays

Deorphanization projects

Identification of relevant targets

Expression of full-length membrane proteins

Functional isolation and stabilization of targets

Conformational antibody development

Vaccine development

High-throughput ligand screening

Structure-based drug discovery

Immunoassays

Deorphanization projects

Identification of relevant targets

Expression of full-length membrane proteins

Functional isolation and stabilization of targets

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Starting from native material or recombinant systems, we succeed with all types of membrane proteins: GPCRs, Ion Channels, Transporters, Receptors and Viral Proteins.